Chinese nursing education levels have developed fast over the past few years. Many nursing educators are devoted to the research of nursing teaching. How to cultivate nursing students, creative thinking is one of the principle researches and has received increasing attention. In the course of nursing teaching, we renewed the teaching design based on the empirical education from nursing basics as follows. The teaching contents are enlarged to make students establish a sense of nursing development and dynamic study. The traditional teacher-centered teaching methods have been replaced by diversified students-centered methods from knowledge to activities. Evaluation of learning effect is developed to be a versatile comprehensive evaluation including students' self-evaluation in accord with the multimedia teaching, group-evaluation in theoretical and discussion classes, and teachers' all-around evaluation. The new teaching design have embodied students' principal role and enhanced their abilities of creative thinking.