The purpose of this study was to investigate the effects of high school students' long-term authentic research projects with Information Technologies (IT) in small groups in and out of school time on their affective dispositions in science. This study was conducted in the context of a three-year NSF project, namely, Translating Information Technology into Classroom (TITiC). A survey consisting of Likert scale items and open-ended questions was administered to 45 students (29 females and 16 males) from Grades 9 to 12. The results of this study showed that on the average 79.37%, 90.83%, and 81.33% of the students developed better attitudes toward, perceptions of, and self-confidence in science, respectively. These increases were further supported by evidence from qualitative data. (Contains 3 tables.)