ACT conducts the only nationwide curriculum survey that empirically identifies current instructional practices and postsecondary expectations in order to develop tests that measure critical skills and knowledge. Every three years, it surveys thousands of middle school/junior high school, secondary, and postsecondary teachers in English/writing, reading (including English language arts and social studies teachers), mathematics, and science to determine what skills and knowledge are currently being taught that are considered important for success at each grade level for college readiness. The present curriculum study documents a gap between what high schools are teaching students in their core college preparatory courses and what colleges want incoming students to know. Responses suggest that college instructors prefer students to have in-depth mastery of a smaller number of fundamental skills, while high schools tend to provide less in-depth instruction on a broader range of topics. The first section of this report provides an overview of the 2005-2006 survey and highlights key findings. This section is followed by the findings for each of four subject areas: English/writing, mathematics, reading, and science. The last section offers conclusions based on the results. The following are appended: (1) Survey Samples, Types, and Response Rates; (2) Statistical Details for Topics and Skills; (3) Test Specifications for the EPAS English/Writing, Mathematics, Reading, and Science Tests; (4) State Standards as Preparation for the Next Level of Learning; (5) Student Preparation for College Today versus in the Past 5-10 Years; (6) Content Topics "Taught" Percentages; (7) ACT's College Readiness Standards: Strand Rankings; (8) Statistical Details for Developmental/Remedial Topics and Skills; (9) ACT Writing Test Rubric; (10) Postsecondary Algebra Readiness; (11) Reading "Not Taught" Percentages by Grade; (12) General Science Skill Items; (13) Ratings of Science Content and Skill Groupings. (Contains 52 tables and 10 figures.)