Eleven years ago, FPG Child Development Institute (FPG) launched a longitudinal study of a little known form of mental retardation known as fragile X syndrome (FXS). The Carolina Fragile X Project has since grown into a multidisciplinary team studying diverse aspects of the condition, ranging from early identification to school performance. The team's research has led to wide understanding of what constitutes the condition, how it can be detected, strategies for intervention, and how to help families cope. This issue of "Early Developments" presents the following topics of interest to parents and professionals working with children who exhibit this genetic disorder: (1) Going the Distance with Fragile X; (2) All in the Family; (3) Screening Newborns for FXS; (4) The Behavioral Challenge; (5) Speech, Language, and FXS; (6) Finding Clues in Family Videos; (7) Fragile X Info Center; and (8) Learn More About FXS at FPG. ["Early Developments" is published three times a year by the FPG Child Development Institute at The University of North Carolina at Chapel Hill. Additional financial support for this issue was provided by FRAXA Foundation and Ronald McDonald House Charities. For other issues of "Early Developments," see ED488881-ED488883.]