This paper describes the trademarked ScienceStart![TM] Curriculum--a science-based early childhood curriculum. The curriculum's major content goal is for children to develop a rich, interconnected knowledge base about the world about them. The curriculum's major process goal is to foster the types of intellectual development that characterize the preschool years, including children's receptive and expressive language skills, self-regulation of attention skills, and problem-solving skills. Following a discussion of the goals and assumptions of ScienceStart![TM], the paper describes the curriculum's characteristics, implementation, and effectiveness. (Contains 19 references and 10 endnotes.) (Author/HTH)