This question and answer guide provides an overview of the research on the origins and pathways of drug abuse, the basic principles derived from effective drug abuse prevention research, and the application of research results to the prevention of drug use among young people. The basic principles derived from drug abuse prevention research are described in simple direct terms so that they can be applied to successfully prevent drug use among young people. Topics covered include: (1) "Risk and Protective Factors"; (2) "Drug Abuse Prevention in the Community"; (3) "Some Research-Based Drug Abuse Prevention Programs"; and (4) "Selected Resources and References." Topics are presented in question and answer format with checklists of prevention principles that apply in particular arenas. Ten prevention programs are described briefly with references for further information; each program is characterized as "universal,""selective," or "indicated." (GCP)