In spite of the growing interest in interaction design, there remains a large user population that needs special interest: users with special needs. These users can dramatically benefit from software that better responds to their interaction needs, not to mention the fact that designing software that takes into account the special needs of such users makes software more easy to use for everyone. This paper presents PERIGRAMMA, a system designed to offer an integrated environment for the support of people with movement or cognitive impairments who offer secretarial support in a modern office environment. The system is currently in its final stage of implementation and offers an easily accessible environment of four applications: a word processor, and e-mail client, a calendar, and a Web publisher. Design considerations of the system, architecture and functionalities, and future work are discussed. (Author/AEF)