This document presents a policy framework designed to foster action to prevent youth victimization and the likelihood that youth living in high risk situations will engage in adolescent and/or later life criminal behavior. It applies to youth ages 12 to 18 years. Eight sections include: (1) "Introduction"; (2) "Policy Background" (a focus on early intervention and models of prevention: transforming knowledge into action); (3) "The Role of the National Strategy on Community Safety and Crime Prevention"; (4) "Key Policy Concerns" (interplay among risk factors at individual, family, and community levels; key challenges; and optimal points of intervention); (5) "Guiding Principles" (e.g., focus on youth and families living in conditions of multiple risk and engage youth and their support systems in the process); (6) "Goals and Objectives" (foster community action, promote conditions that will prevent youth victimization, and the probability of current or later life criminal behavior); (7) "Components" (public awareness and education, comprehensive strategies and models, tools and resource development, and research and knowledge development); and (8) "Funding Overview." Two appendixes present data on crime prevention and childhood experiences, situations, and potential adverse consequences; factors that contribute to positive outcomes for children and youth; and the funding focus. (SM)