Local school-to-work intermediaries and national industry associations share the goal of organizing employers to improve learning and career opportunities for young people. Each type of organization has much to offer the other. Local school-to-work intermediaries perform the following essential functions: convene local employers and other leaders; broker and/or provide services to workplace partners, educational institutions, young people, and the youth-serving system; ensure the quality and impact of local efforts; and promote policies to sustain effective practices in particular communities or regions. National industry-based organizations can aggregate the resources and energy of their members to achieve the following goals: recruit new workers into an industry; design programs that prepare young people for a particular industry and for career success extending beyond any one industry; create and disseminate curricula and standards for programs; and create and promote credentials of value to employers. National industry associations offer the following items: quality materials and programming; respected credentials; accelerated dissemination; and national- and state-level advocacy. Local school-to-work intermediaries offer the following items: access to key employers and leaders; local knowledge; pilot sites; and a local voice for advocacy. Greater collaboration between local school-to-work intermediaries and national industry association's promises significant benefits but will require overcoming several challenges, including the following: (1) school priorities often differ those of industry; and (2) local and national groups sometimes compete with employers and other key individuals at the local level. (MN)