This booklet describes the DO-IT Pals program, a University of Washington program designed to encourage high school students with disabilities to explore careers in science, engineering, mathematics, and technology and learn more about how to prepare to enter these fields of study and employment. The program provides students with information about college entrance requirements, application procedures, college survival skills, internships opportunities, resume and interviewing tips, and additional resources to help them through the transitions to college and employment. Students participate in the following activities: frequent electronic communication and personal contacts with mentors who support students' academic, career, and personal goals; use of the Internet to explores academic and career interests, make friends and motivate each other to achieve goals; and application their skills and knowledge to design and complete independent or team projects based on their interests. The role of the mentor is described, along with the technology needed to participate in the programs. (CR)