The Health Sciences and Technology Academy (HSTA), administered through West Virginia University, provides professional development to science teachers who partner with higher education faculty in a science and math enrichment program for financially disadvantaged African American students. This program focuses on human nutrition and has incorporated the use of graphing calculators. This paper describes the application of graphing calculators to several sample human nutrition data sets. (Contains 11 references.) The calculators facilitate understandings about experimental design and other cross-disciplinary concepts and how science and math connect to human health. This project provides one context for secondary teachers and teacher educators to collaborate towards integrating science and math instruction. (WRM)