This TIP, on the best practice guidelines for treatment of substance use disorders, was compiled from an increasing body of research literature that documents the effectiveness of brief interventions and therapies in both the mental health and substance abuse treatment fields. It links research to practice by providing counselors with up-to-date information on the usefulness of these treatment forms for selected subpopulations of people with substance abuse disorders or for those at risk. The manual states that brief interventions and therapies are less costly, yet effective, in substance abuse treatment. Brief interventions have been found to be effective for a range of problems; they can greatly improve substance abuse treatment by making it available to a greater number of people and by tailoring the level of treatment to the level of client need. This TIP includes sections on brief interventions and therapy in substance abuse treatment, along with sections on brief therapies in the fields of cognitive-behavioral, strategic/interactional, humanistic and existential, psychodynamic, family, and group counseling. Appendixes include "Bibliography,""Information and Training Resources,"" Glossary,""Health Promotion Workbook,""Resource Panel," and "Field Reviewers." (Contains 43 figures and approximately 450 resources.) (JDM)