This report discusses the outcomes of a South Dakota project designed to develop and validate a natural support system involving typical co-workers providing on the job training and support to individuals with disabilities. The Co-Worker Mentoring in Supported Employment (CMSE) project had the following outcomes: (1) job development activities resulted in 34 individuals with severe disabilities placed in community-based jobs; (2) 32 co-worker mentors from local businesses provided training and follow-along services to individuals served in the project; (3) CMSE and participating agency staff were instrumental in the development of transition plans which formalized job development, job placements, and follow-along responsibilities for student services in the project; (4) CMSE staff increased the number of community based vocational placements for students and adults with disabilities, the number of businesses where placements occurred, and the types of job placements; (5) CMSE staff provided training and technical assistance to co-worker mentors on an as needed basis to assist with individual participation needs; and (6) information regarding the CMSE model was disseminated. Results from the project indicate the program was effective in increasing community-based vocational placements for students and adults with disabilities. The report outlines project objectives and accomplishments. (CR)