The National Institute of Mental Health reported in 1998 that suicide in the United States is the third leading cause of death among young people, and that they are the only age group whose mortality rate has increased due to suicide during the last 20 years. The United States Territory of Guam has also experienced an increase in adolescent suicide. This paper describes two levels of school-based suicide prevention programs. The primary prevention program aims to deter the problem from occurring in individuals and encourages ways to deal with life. The secondary prevention program works to identify problems at their initial stage in order to shorten the duration of the problem and lessen their intensity. The primary prevention programs are curriculum-based and are geared towards fostering decision-making skills and developing a positive self-image. Secondary prevention programs rely on student self-referral, peer referral, or actual incidents and work towards defusing already problematic conditions. The paper includes several recommendations for an effective school-based suicide prevention program for Guam. It recommends that Guam augment its prevention program with Zuni Life Skills Development Curriculum since Zuni culture is similar to Guam culture which fosters interrelations and group cohesiveness. (Contains 19 references.) (JDM)