This document comprises two issues of a new UNESCO newsletter addressing topics related to adolescent well-being in the Asia-Pacific region, particularly reproductive and sexual health. Both issues contain news from the region on various initiatives related to adolescent health and education, as well as Web links and publications on the subject. Each issue also contains a feature addressing program guidelines. June's feature is "What Makes Sex Education Programmes Succeed," while December's feature is "Effective and Ineffective School-Based Sex and HIV/AIDS Education Programmes." Countries covered in the issues include Bangladesh, Cambodia, China, India, Indonesia, the Pacific Islands, Pakistan, Philippines, Thailand, Vietnam, Bhutan, Maldives, Nepal, and Sri Lanka. The brief articles provide various statistics, program descriptions, guidelines, concerns, and recommendations related to improving adolescent reproductive health and general well-being in this region. (EV)