This study evaluated professional outcomes for graduates of the 32 programs supported by the National Institute of General Medical Sciences under the Medical Scientist Training Program (MSTP). Specifically, it evaluated the success of MSTP graduates in establishing research careers and the types of careers and research activities followed compared to graduates of other combined-degree or Ph.D. programs. Data were from National Institutes of Health data bases and curricula vitae provided by graduates of MSTP programs and members of comparison groups. Findings indicated that MSTP graduates are more likely than comparison groups to have received postdoctoral research training support, to hold academic appointments, to have received research support, to have applied for and obtained NIH research grants, and have more total publications and more recent publications. Analysis indicated MTSP graduates are most similar to non-MSTP M.D.-Ph.D.s from the same institutions. Overall, the comparison suggests that MTSP graduates more closely integrate their research activities with medical practice. Individual sections of the report provide background information, detail on the study design, and present findings on educational and career outcomes and professional and research activities. Four appendices include a list of academic department classifications, additional methodology information, definitions and criteria, and statistical tables. (Contains 32 references.) (DB)