This report consists of information gathered from in-person surveys concerning substance abuse with adult residents (n=1,665) living in the Texas-Mexico border cities of Brownsville, El Paso, Laredo, and McAllen and with residents (n=504) of 51 different colonias in Hidalgo and Cameron counties (colonias are rural, unincorporated neighborhoods characterized by substandard housing and utility services). Current treatment needs and the prevalence of substance abuse within the group is discussed. Participants are compared to other populations including adults in other parts of Texas, Hispanics nationwide, and citizens of Mexican border cities. Acculturation and its relation to substance abuse is examined. Discusses driving while intoxicated, mental health, drug trafficking, availability of drugs and alcohol, family dynamics and problem gambling. Looks specifically at substance use and misuse in the colonias. Provides 22 charts and 29 tables illustrating results of the surveys. (Contains 80 references.) (MKA)