This handbook contains guidelines for setting up a workplace literacy project through a partnership between business and an educational partner. It is based on the experiences of a workplace literacy partnership of Bakery Europa, Straub Clinic and Hospital, and the University of Hawaii. Information is provided on the following six topics: (1) building successful partnerships (duties and responsibilities of educational and business partners, composition and duties of advisory committee); (2) identifying workplace literacy needs (general and business-specific needs); (3) facilities; (4) instruction (goals, content, format, methodology, scheduling, and assessment); (5) recruitment (methods and incentives); and (6) evaluation (recordkeeping and effects on workplace productivity). (KC)