This paper describes characteristics of and educational implications for children with Hunter's syndrome, a rare, genetic lysomal storage disorder resulting from an absence of the enzyme iduronate-2-sulphatase. Boys born with this sex-linked disease are born with little or no clinical manifestations, but generally are diagnosed by the age of three due to developmental delays. This progressive disorder results in early mortality and presents a myriad of considerations for special education. The paper addresses the history of the disability and its symptoms, including cognitive disabilities, speech development, eating problems, ear infections, and respiratory problems associated with the disorder. It notes that progressive physical and cognitive disabilities require special educators to work with a team of professionals to provide these children an appropriate education and a better quality of life. Behavior problems of the children with Hunter's syndrome are also described and include hyperactivity and aggressive behavior. Strategies are provided for encouraging social relations among students with disabilities and their typical peers. The importance of parents as part of the collaborative team to ensure successful education of these children is stressed. (Contains 17 references.) (CR)