This handbook, which is intended for K-12 teachers in Colorado, explains how to integrate academic content standards and assessments with workplace competencies and school-to-career activities. The handbook is divided into four sections. The first presents the Colorado General Workplace Competencies, which describe the skills and knowledge students need to be successful in most careers and in college. The competencies are organized into five categories: communication; organization; thinking; technology; and worker qualities. The second section, titled "Opportunities for Success," offers guidelines for educators as they help special populations of students meet academic content standards and participate in school-to-career opportunities. Section 3 features grids providing examples of how the Colorado General Workplace Competencies cross-reference with the Colorado Model Content Standards for mathematics in grades K-4, 5-8, and 9-12. Each grid is followed by examples of classroom strategies combining a specific academic content standard, career development activity, general workplace competency, and assessment strategy. Quotations included throughout the handbook provide the perspectives of Colorado educators, business leaders, and students on integrating workplace competencies and academic content standards. A sample rubric constitutes the fourth section. Concluding the handbook are the addresses of Colorado's six school-to-career regional resource centers. (MN)