This study presents a preliminary exploration of emotion regulation in a sample of 20 children (ages 3-18 years) with Down Syndrome. Three aspects of emotion regulation (modulation, organization, flexibility) were predicted from emotion variables (affect intensity, affective expression, and autonomy-curiosity and motivation) in backward regression models. Emotion regulation was rated by mothers and teachers. Context variable was represented by school or home setting. The results suggest that: (1) the emotional experiences of children with Down Syndrome may be more intense than previously believed; (2) children's emotional behavior is viewed differently by context and rater; and (3) each component of emotion regulation is predicted by a unique configuration of emotional behavior. (Author/EMK)