This handbook is designed for college teachers who want to explore new ways to enhance student learning. The handbook draws on the knowledge of teachers and scientists with extensive experience in the natural sciences and a keen interest in effective science teaching, and is appropriate for anyone teaching undergraduate science. This handbook provides information on successful teaching practices in a variety of science courses and current research in undergraduate science education. Practical guidelines for experimenting with and changing teaching are also included. Topics covered include general principles of how teachers teach, lectures, discussions, collaborative learning, scientific research as a learning model, misconceptions as barriers to science learning, evaluation of teaching and learning, testing and grading, choosing and using instructional resources, getting to know the students, societies and organizations involved with science teaching and science-related issues, periodicals pertaining to undergraduate science education, and laboratory issues. Contains 143 references. (DDR)