Preschool children need direct involvement with science content hands-on experiences that involve them in gathering, organizing, analyzing, and evaluating. This paper describes how to create a science area in a preschool classroom. The paper delineates the equipment needed to maintain a mentally stimulating environment for young children. It also discusses the importance of hands-on science activities, lists themes appropriate for young children, and discusses the teacher's role as a facilitator of knowledge development. Five science activities are described: (1) observing that magnets attract some objects and not others; (2) using paper, petroleum jelly, and a magnifying glass to observe air pollution; (3) using peanuts to practice observing, measuring, classifying, and predicting; (4) using celery and food coloring to view the transport of liquid throughout a plant; and (5) identifying objects through the sense of smell. Contains 13 references. (Author/KB)