This brief paper summarizes requirements of the Americans with Disabilities Act (ADA) of 1990 related to workplace accommodations for persons with musculo-skeletal disorders. The following topics are addressed: (1) the relevance of the ADA to people with musculo-skeletal disorders; (2) employment provisions of the ADA to protect individuals with such disabilities during the job application process (including prohibition of questions regarding an applicant's medical history); (3) what is meant by "reasonable accommodation" under the law; (4) examples of accommodations for people with musculo-skeletal disorders, including engineering and administrative accommodations; (5) relevance of the law to employees returning to work after a workers' compensation situation; (6) ways to maximize the employee's potential for success; and (7) long-term financial and other advantages to the employer of compliance with the ADA. A listing of eight resources is provided. (DB)