The brain is the seat of intelligence, the interpreter of senses, and the controller of movement. Research efforts on the brain have increased dramatically in the past 10 years; some of the more promising areas of brain and behavioral sciences research are reported here. The research was performed by 22 separate Federal member organizations and covers nine separate areas that could form the basis of an integrated program for brain and behavioral sciences. The text opens with a description of cross-cutting program areas and presents findings in basic research, in technology, and in international activities. Drugs and the brain and the role of addiction are covered in the first specialty area, followed by research findings devoted to aging and the brain. Section 3 profiles findings on human behavior and mental disorders, and section 4 describes research on damage to the brain and spinal cord. Communication and sensory disorders are treated in the following section. Sections 6 and 7 examine the development of the brain and detail the intricacies of learning and memory. Section 8 investigates rehabilitation and restoration of brain function and section 9 outlines environmental impacts on the brain. A chart, which summarizes the nine topic areas, appears in the back. (RJM)