Following an overview and background information on Human Immunodeficiency Virus/Acquired Immune Deficiency Syndrome (HIV/AIDS), this paper is divided into six sections. The first section discusses the extent of the problem and educational implications for children, adolescents, and young adults. The second section, Calls to Action, provides information on calls for action that have issued from schools, parents, institutions of higher education, community organizations, national and state government agencies, media, and professional groups. The third section addresses the need to plan prevention strategies. Specific topics in this section are: primary, secondary, and tertiary prevention goals and strategies; comprehensive school health education and programs; and characteristics of effective HIV/AIDS and health education curricula. The fourth section notes implementation barriers at the classroom, administrative, and school-community collaborative levels. The fifth section deals with prevention within institutions of higher education and schools, colleges, and departments of education, through preparation of future educators and through partnerships with campus, school, and community groups. The sixth section outlines the AACTE/CDC Project: Build a Future without AIDS. The Joint Statement on School Health by the Secretaries of Education and Health and Human Services is appended. (Contains 10 figures and 61 references.) (JLS)