Secondary data sources, including the ERIC and National Dropout Prevention Center databases, were reviewed to identify programs and strategies effective in keeping at-risk youth in school and helping them make successful school-to-work transitions. The dropout prevention model that was identified features a system of prevention, mediation, intervention, and recovery activities beginning with preschool youth and leading to adulthood. A review of 20 exemplary vocational programs for special needs students established the following elements as critical to effective transition programs: strong administrative leadership/support; formalized articulation and communication; individualized curriculum modifications and appropriate instructional settings; comprehensive support services (including ongoing career guidance/counseling); and occupational experience. Nine exemplary programs representing diverse geographic regions and institutional settings were identified and profiled. The programs focused on the following groups: economically disadvantaged youth; youth with physical/learning disabilities; females and minority youth; youth with limited English proficiency; underachieving/unmotivated youth; chronically truant youth; substance-abusing youth; juvenile offenders; and tech prep students. (Contains 29 references. Appendixes constituting approximately 50% of this document contain the following: profiles of the 9 exemplary programs; standards/quality indicators for evaluating programs for at-risk students; glossary; and annotated bibliography of 13 organizations and 19 publications addressing the needs of at-risk youth.) (MN)