This report reviews and compares the impact of university support policies in Ontario to those of Quebec, Alberta, and British Columbia and proposes a framework to regenerate the research infrastructure of Ontario universities. It identifies erosion in Ontario's comparative and competitive position within Canada though Ontario still performs about 40 percent of Canada's university research. Specific trends in research capacity are analyzed for sponsored research, funding and grants of the National Sciences and Engineering Research Council, Medical Research Council funding, Social Sciences and Humanities Research Council funding, sponsored research by academic staff, and provincial share of PhDs granted. Major challenges are identified in the areas of research infrastructure, federal and provincial responsibilities, the nurturing of new researchers, and finding the balance between publicly and privately supported research. The proposed framework for the Ontario Government urges: (1) a formal policy statement recognizing the research mission of universities; (2) explicit support for research infrastructure; (3) efforts to attract and retain new faculty; (4) the harnessing of university expertise for socioeconomic development; (5) complementarity of Ontario efforts with those of the federal government; and (6) development of Ontario universities as a network of complementary institutions. A summary of the research policies in Quebec, British Columbia, Alberta, and Ontario is included. (JLS)