This report presents the first results from the 1995 National Household Survey on Drug Abuse, an annual survey conducted by the Substance Abuse and Mental Health Services Administration. The survey provides estimates of the prevalence of use of a variety of illicit drugs, alcohol, and tobacco, based on a nationally representative sample of the civilian noninstitutionalized population aged 12 and older. In 1995, 17,747 people were interviewed for the survey. An estimated 12.8 million Americans were current illicit drug users, a figure that represents no change from the 1994 level, but which is lower than the 1979 high when the number was 25 million. Significant increases in past month marijuana and hallucinogen use occurred among youth between 1994 and 1995. In 1995, 52% of the population had used alcohol in the past month, but there were no changes in the rate of alcohol use between 1994 and 1995. An estimated 61 million Americans were current smokers in 1995, a smoking rate of 29%. Five appendixes discuss survey methodology and data and present references and detailed tables. (Contains 12 figures, 41 tables, and 58 references.) (SLD)