This instructor's manual is designed to improve the instructional support program for Writing 139, an interdisciplinary advanced composition class at the University of California, Irvine taught primarily by graduate student teaching assistants. After a brief history and overview of the course, the manual presents sections that address the rationale for the course; frequently used books, articles, and videos; course specifications and policies (including page lengths, grammar, style, and rewrites); teaching strategies (including in-class diagnostic assignments, library research assignments, student reports, peer editing, group activities, debates, and games); design of essay assignments; and use of electronic mail and the Internet. Appendixes present a chapter by chapter guide to Evelyn Fox Keller's "Reflections on Gender and Science" (by Kathy Keating); a (partially) annotated bibliography of frequently used texts; and an evaluation form. (RS)