This report provides an analysis of those portions of the Americans with Disabilities Act (ADA) and related legislation relevant to the career preparation and employment status of individuals with cognitive impairments. It reviews government-sponsored evaluations and professional research in specific areas of labor and education and reports on a national survey of 73 program providers about individualization practices in transition and supported employment programs. The report's general findings are as follows: (1) educational and employment preparation program outcomes for individuals with disabilities in the United States are not promising; (2) efforts regarding compliance with reasonable accommodation requirements of the ADA Title I have focused on architectural modifications rather than other work site modifications (e.g., programmatic); (3) a well-articulated process of individualization and a bank of useful accommodation practices exist and can be used for employees with cognitive impairments; (4) transition and supported employment programs often incorporate useful accommodation strategies at the worksite; and (5) greater coordination with the hundreds of relevant federal and state programs is needed. Recommendations for policymakers, business and industry leaders, school system personnel, and the disability community are offered. Appendices include the questionnaire used in the survey of program providers and a description of the National Council on Disability. (DB)