This paper presents findings of a study that examined Mississippi public school superintendents' attitudes toward persons with Acquired Immune Deficiency Syndrome (AIDS) or Human Immunodeficiency Virus (HIV). A survey mailed to 153 Mississippi superintendents yielded 107 returns, a 70 percent rate. The instrument was called the "Superintendents' Attitudes Toward Persons with AIDS in Mississippi Public School Districts." The sample was predominantly comprised of white males. Overall, the superintendents showed a moderate attitude, neither negative or positive, toward persons with AIDS. Most (66 percent) had not participated in AIDS-education workshops, had not established AIDS-awareness programs in their school districts (over 80 percent), and had not encountered persons with AIDS or HIV in their school districts (98 percent). Gender, age, ethnicity, educational level, geographic location, and years of experience had no significant effect on the administrators' attitudes. It is recommended that school districts adopt an AIDS policy; develop initiatives that will motivate students to change risky behaviors; research and implement AIDS-education programs on a continuing basis; and require inservice training for school administrators. Fourteen tables are included. A copy of the questionnaire and study correspondence are included in the appendices. (Contains 29 references.) (LMI)