The National Science Foundation (NSF), in collaboration with 24 states and one territory, is engaged in a multi-year effort to improve the quality of mathematics, science, and technology education for all students in a systemic way. The goal of the Statewide Systemic Initiatives (SSI) is to develop broad strategies for coordinating or aligning state-level initiatives and policies in curriculum, assessment, teacher education, professional development, and other key components of educational change. In order to assist other states seeking to implement system-wide reform, this report provides a brief glimpse of some of the SSI strategies that are positively changing teaching and learning in mathematics, science, and technology education. The strategies included are in the following areas: addressing the needs of policy makers, enriching cooperation and collaboration among educators, and sustaining the scale-up of reform. (JRH)