This survey examined the behaviors associated with the six leading causes of death or disability in one state's high school youth. Participants were 2,439 9th-12th grade students. Results identified alcohol as the drug most frequently used by high school students, with over half of students having used alcohol by their senior year and almost half having had at least one drink in the month prior to the survey. Nearly 25 percent reported binge drinking--white students were almost twice as likely to binge drink as black students. More than one-third of students had ridden with a driver who had been drinking with one-fifth of males and one-tenth of females admitting to drinking and driving. For tobacco use, males and females appeared nearly equally likely to smoke cigarettes but white males made up almost all of smokeless tobacco users. For illicit drug use, black students were less likely than white or "other" students to have used most types of drugs. White males reported the use of almost all substances to a greater degree than other students. Comparisons to earlier reports suggest that younger adolescents are less likely to consider the use of alcohol, tobacco, or other drugs to constitute risky behavior. Contains 22 references. (RJM)