This career planning guide is intended for college students with disabilities who desire careers in science, mathematics, or engineering. The booklet reflects the experiences and advice of 286 individuals with disabilities who are in these careers or preparing for them. The first section focuses on the personal autonomy available in the college setting. The second section suggests sources of information about available college support services, financial aid, and suggestions to facilitate adjustment. A checklist allows the student to assess needs for his/her specific disability. Next, choosing a major is discussed as well as making connections with faculty members, students, and other people with disabilities. Assistive technology for students with vision impairments, hearing impairments, and mobility impairments is addressed and the importance of being familiar with federal laws that protect students with disabilities is stressed. The following section focuses on communication, including communicating one's special needs and the importance of making contacts with other people. The final section notes the importance of maintaining a sense of humor and achieving real competence in one's chosen field. Interspersed throughout the booklet are photographs of successful individuals with disabilities and quotes giving their advice. (DB)