The Howard Hughes Medical Institute has as a major focus the improvement of science education at all levels. Each year the institute provides grants for competing organizations whose aim is educating the public in science and/or biomedical research. This document contains the proceedings of a conference that provided a forum for 98 representatives from institutions (public and private research universities, historically black institutions, and four-year liberal arts colleges) receiving undergraduate awards in the 1991 and 1992 competitions to convene and discuss institutional strategies for enhancing undergraduate science education. Topics discussed are as follows: (1) systemic reform; (2) enhancing the educational experience of American Indian students; (3) providing science education opportunities for traditionally underrepresented groups; (4) interdisciplinary studies in biochemistry and molecular Biology; (5) faculty development and high school enrichment; (6) computer use for the study of atomic, macromolecule, and organismic structures; (7) science curriculum development; (8) partnerships in education; and (9) teaching and learning strategies. Also included are: program profiles at selected institutions; four appendixes which contain details about the awardee institutions and a list of meeting attendees; a list of grants publications; lists of Howard Hughes Medical Institute trustees, officers, and principal staff members; and a subject index. (ZWH)