This directory begins with an overview of the contemporary status of American Indians living in the central Appalachian region--Kentucky, Tennessee, Virginia, and West Virginia. Although there are no federally recognized tribes in this area, there are small Indian groups living on or near their ancestral lands in Virginia and Tennessee. The Indian population is even more dispersed in Kentucky and West Virginia; however, there are many people with Cherokee and other tribal ancestry, as well as Indian people from other parts of the country who have migrated to these states. The directory includes contact information for 60 tribal, educational, historical, social-service, and advocacy organizations in the region that are committed to preserving American Indian culture, providing needed services to American Indians, and enhancing the educational opportunities of American Indians. Each listing includes address, telephone number, and a description of organizational objectives and services. (LP)