An interactive videodisk (IVD) program was developed to reinforce learning of the biological concept of protein synthesis for high school students. The laser videodisc "The Living Textbook Life Science" was the source of frames, and the authoring system of G. Smith was used to create the disc. The interactive program was designed to make the material relevant to the learner at the tenth-grade level. Four high school students pilot tested the program, and 43 students (19 ninth graders, 22 tenth graders, 1 eleventh grader, and 1 twelfth grader) tested the completed version. After using the program and completing its multiple choice test, students completed essays about the content. Students did well on the multiple choice test, which they were able to score immediately, but not as well on the essays. Students responded well to the program and were positive about its usefulness. Students who took more time with the program achieved higher posttest scores. The program appears to be an effective method to help students understand the concept of protein synthesis. Thirteen appendixes present supplemental information, including the multiple choice questions. Six tables present study findings. (Contains 34 references.) (SLD)