This curriculum guide aims to help teachers and students in Catholic schools and parish religious education programs to: (1) become more deeply rooted in Gospel values and Catholic moral teaching; (2) understand the HIV virus and the disease which it causes, Acquired Immune Deficiency Syndrome (AIDS); and (3) develop decision-making and leadership skills to protect themselves and others from HIV and AIDS. The program has two components--a teacher's manual and an implementation guide. The manual provides teacher's materials (student hand-outs, transparency masters, lesson plans, activities) and methodology, a scope and sequence chart of HIV/AIDS-related learning objectives, and suggested, age appropriate lessons for K-12 students. The teacher's manual also includes: articles used for lessons and background--"Address at Mission Dolores" by Pope John Paul II; "AIDS: Time for a Moral Renaissance" by Cardinal Basil Hume; "A Challenge and a Responsibility" by Cardinal Joseph Bernardin; and "Human Viruses: Tape Cassette Analogy" by Lawrence A. Hunt; a list of universal precautions to prevent the spread of infections diseases in school settings; and a glossary of terms. The implementation guide provides ideas for preparing a teachers' inservice program, suggestions for planning a parents' session, and an annotated list of resources. (LL)