This guide offers a framework for making sound decisions among the range of available choices to maximize the educational opportunities of integrated students with disabilities. The framework permits programs to be classified according to their approaches to intervention and general characteristics. A planning process is presented for use in program review, selection, and implementation. Sixteen programs are then described along the key dimensions presented in the decision-making framework, to demonstrate how program information can be extracted and synthesized so that informed decisions can be made. These dimensions include target population, implementation considerations, program effectiveness, and costs. The programs include: High/Scope Curriculum, Strategies Intervention Model, Tactics for Thinking, Direct Instruction, Mastery Learning, Learning Styles, SUCCESS, Student Team Learning, Classwide Student Tutoring Teams, Adaptive Learning Environments Model, Vermont Consulting Teacher Model, Teacher Assistance Team, Project RIDE, North Carolina Lead Teacher Model, Comprehensive Local School, and Coalition of Essential Schools. (Each program description contains a list of references.) (JDD)