The presence of the computer in the classroom is no longer considered an oddity; it has become an ordinary resource for teachers to use for the enhancement of instruction. This paper presents an examination of software infusion, i.e., the use of computer software to enrich instruction in an academic curriculum. The process occurs when a chosen software is incorporated within an overall teacher designed and implemented lesson plan. Some impediments to software infusion are discussed: (1) lack of quality software; (2) lack of sufficient software and/or hardware; (3) high cost of hardware and software; and (4) lack of teacher training. The elements of software infusion (relationship to objectives, integration into lesson design, range of applications, range of utilization strategies, use of specific capabilities of the computer, and computer literacy benefits) are described, and examples of software infusion in actual practice, as derived from the California Framework and Model Curriculum Guides in the specific subject areas of science, mathematics, history, and social science are included. (LL)