This document presents summaries of the 147 demonstration grant projects sponsored by the federal Pregnant and Postpartum Women and Their Infants initiative, which is jointly funded by the Center for Substance Abuse Prevention and the Maternal and Child Health Bureau. This substance abuse prevention grant program, the largest federally funded program of its kind to date, focuses on the development of innovative, community-based models of drug prevention, education, and/or treatment targeting pregnant and postpartum women and their infants. Services include prenatal, postpartum, and/or infant services. Most of the projects also provide direct services such as case management, parenting classes, and referrals to drug and alcohol programs. Many of the projects have developed outreach strategies and community networks of providers. Numerous projects are also involved in training providers and offering prevention education at the community level. The projects are carried out by a variety of agencies, with health departments and community-based organizations administering more than half of them. The projects reach a high number of low-income African American and Hispanic families. Crack/Cocaine is the drug most frequently addressed by these projects, followed by alcohol and polydrugs. The project summaries provide information about the projects' goals and objectives, methodology, evaluation, and experience to date, as well as names, telephone numbers, and office addresses of contact persons and directors. (JDD)