This review of effective practices in state-wide systems change was conducted as part of the PEERS (Providing Education for Everyone in Regular Schools) Project, a 5-year collaborative systems change project in California to facilitate the integration of students with severe disabilities previously at special centers into services at regular school sites and to facilitate the integration of students in special classes in regular schools into general education. A "Systems Change Review Tool" was developed in cooperation with major systems change efforts in 16 states. Critical activity areas identified and verified by this measure constitute the main sections of the manual, addressing: (1) Facilitating Locally Owned Change (Ann Halvorsen); (2) Increasing Awareness and Knowledge of Best Practices (Ann Halvorsen); (3) Supporting the Implementation Effort (Morgan Alwell); (4) Promoting Collaboration (Morgan Awell); (5) Dissemination Activities (Morgen Alwell); and (6) Evaluation Change (Patricia Karasoff). Within each section, information is provided on: a rationale for the activity's inclusion in a comprehensive approach to systems change; a narrative describing relevant strategies with examples and case studies; and an annotated listing of selected strategies utilized across the states within each critical activity area. Appendices provide a directory of systems change projects, a list of products from system change projects, and sample systems change discrepancy analysis worksheets. (Contains 59 references.) (DB)