Asian-American, Hispanic-American, and Anglo college students were compared on measures of psychological well-being. In Study 1, 47 Asian-American and 89 Anglo male and female undergraduate students were compared on a variety of psychological scales. The main difference found between groups was that Asian Americans scored higher on avoidance than did Anglos. It was hypothesized that acculturation may have obscured some ethnic differences. To control for this, the Asian-American group was divided into two subgroups assumed to differ in degree of acculturation based on whether the primary language at home was English (N=21) or not English (N=25). Lower avoidance, loneliness, and neuroticism, but high esteem scores, were found among Asian Americans whose primary home language was English in comparison to those for whom the native language was used at home. In addition, Asian Americans from homes where English was spoken had scores on psychological well-being variables comparable to those found in Anglo students. A similar comparison of Hispanic-American (N=37) students and Anglo students (N=89) showed that Hispanics, as a whole, differed from Anglos only in having lower agreeableness scores. More highly acculturated Hispanics (N=22) and Anglos were both less avoidant and higher in seeking social support than were less acculturated Hispanics (N=15). (Author/NB)