This document is written to encourage college faculty to use a student-centered, activity-related, approach to science instruction. Suggestions are provided for methods that can be used by faculty and administrators to develop alternatives to lecturing. The major sections of this document include the following: (1) Is There an Alternative to Lecture? (2) Labs: The Place To Experiment; (3) The Doubts; and (4) How To Get Some of These Changes Moving. The following alternatives to lecture are described: question asking, hiding the textbook, putting the students in the center of the class, letting students do experimental analysis, and using projects. (PR)