This practicum report describes the implementation and evaluation of a substance abuse prevention curriculum in a Florida preschool. It was expected that, as a result of the implementation of the curriculum, children would improve in their ability to identify drugs; would increase their self-esteem; and would improve their peer relations. It was also expected that teachers would rate the curriculum as appropriate and easy to implement. Pre- and posttest measures gauged children's responses to pictures of drugs, of faces of children with various emotions, and of children interacting. A survey measured teacher attitudes. The curriculum, which involved interventions over a 1-month period, included presentation of information about drugs and activities designed to enhance children's self-esteem and peer relationships. Results indicated an increase in children's ability to identify drugs and in the number of children who chose a picture of a happy face as indicating their feelings about themselves. Teachers rated the curriculum as appropriate and easy to implement. A list of 21 references is provided. Appendices include a copy of the preschool substance abuse prevention curriculum, the teacher evaluation survey results, and other materials related to the curriculum and the practicum. (BC)