This guide deals with the use of computer technology with students who have moderate cognitive abilities. It defines moderate mental retardation and notes the decreasing incidence of mental retardation. It describes characteristics of students with moderate cognitive abilities and examines the role of technology in the educational program of these students. The importance of relating technology applications directly to students' educational objectives is noted. Training on "daily use/low-tech" devices, such as copy machines, calculators, and answering machines, is described as increasing these individuals' skills for independence, employability, and leisure activities. Suggestions are offered for using certain technological devices such as camcorders and educational software as an intervention strategy to achieve students' educational goals. Guidelines are presented for achieving an effective match between the learner and the technology, for selecting software, for determining necessary keyboard adaptations, and for making use of emerging technologies. The guide concludes with a list of organizational, periodical, and product resources. (JDD)