This guide is designed to assist local educators and community leaders in the development and implementation of a comprehensive, integrated curriculum in health and safety education for students in grades K-12. The program is designed to develop critical thinking, problem-solving, and decision-making skills, and to provide the necessary information to motivate students to protect, maintain, and improve their health. Ten chapters are presented as follows: (1) Comprehensive Health Education; (2) What Is Health and Safety Education?; (3) Curriculum Development Process; (4) Philosophy and Goals; (5) Organization of Topics; (6) Learning Objectives--A Process; (7) Selecting Learning Objectives; (8) Curriculum Evaluation; (9) Related Issues; and (10) Reinforcing Health Concepts. Five appendixes provide an evaluation checklist, an implementation model, text of relevant legislation, a list of criteria and program characteristics to help administrators choose effective drug prevention programs and speakers, and a set of sugestions on how to answer difficult questions. (LL)