This report describes current research activities and future plans of the Pediatric, Adolescent, and Maternal AIDS (PAMA) Branch of the National Institute of Child Health and Human Development's Center for Research for Mothers and Children. The mission statement of the Branch notes that PAMA develops, implements, and directs a wide range of domestic and international research activities for the study of the pathogenesis, epidemiology, natural history, and risk factors and co-factors of human immunodeficiency virus (HIV) and related retroviruses in prenant women, mothers, infants, children, adolescents, and the family unit as a whole; and develops and supports clinical trials of specific and adjunctive therapy for this population. In addition, the Branch works toward providing a more precise understanding of the modes of transmission of HIV and related retroviruses in this population and interacts to render treatment and services to the HIV population and to provide full coordination with other programs and other federal and non-federal research agencies. Activities of the Branch are organized around five areas of emphasis: (1) epidemiology and natural history of HIV infection in pregnant women, mothers, infants, and children; (2) therapeutic research in HIV infection in children and pregnant women; (3) pediatric and maternal biomedical HIV-related research issues; (4) adolescent HIV infection and disease; and (5) public health policy issues in maternal and pediatric AIDS. The Branch's budget for fiscal year 1990 is provided. (RH)