This report discusses how computers are being used in high school science classrooms. For this report, four high school science teachers were interviewed. The approach to science instruction described in these four interviews deals with the areas of scientific and technological literacy, making science learning fun and attractive, and stimulating the use of higher-order thinking skills. All are involved in the use of computers to enhance science instruction through activities based on microcomputer-based laboratories (MBL). The four subjects are participants in one of two projects dedicated to such computer application, LabNet and StarNet. Both LabNet and StarNet, projects of the Technical Education Research Centers (TERC), and MBLs are described. The characteristics common to all four of the interviewed teachers are discussed. The advantages and disadvantages of taking this approach are presented. (KR)